Search results for "Gynecologic pathology"

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Microarray analysis in sperm from fertile and infertile men without basic sperm analysis abnormalities reveals a significantly different transcriptom…

2007

Sperm analysis following World Health Organization guidelines is unable to explain the molecular causes of male infertility when basic sperm parameters are within a normal range and women do not present gynecologic pathology. Consequently, there is a need for accurate diagnostic tools in this area, and microarray technology emerges as promising. We present, for the first time, preliminary results of a comparison of sperm mRNA expression profiles between fertile and infertile men with normal semen parameters, discovering profound discrepancies between groups, with potential diagnostic and therapeutic possibilities.

InfertilityMaleSemenBiologyMale infertilityTranscriptomeAndrologyAntigens NeoplasmSemenmedicineHumansTrypsinRNA MessengerInfertility MaleOligonucleotide Array Sequence Analysisurogenital systemGynecologic pathologyGene Expression ProfilingObstetrics and GynecologyDNAgamma-Glutamyltransferasemedicine.diseaseSpermSpermatozoaGene expression profilingFertilityReproductive MedicineGene chip analysisTrypsinogenApoptosis Regulatory ProteinsFertility and sterility

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